Comparison of transdermal and oral estrogen therapy in girls with Turner's syndrome. Oral estrogen was given at a dose of 1. The subjects received one form of estradiol for one month, and after a one month washout period, received the other form.
The estrogen patch (oestrogen patch) is a delivery system for estradiol, which is used as hormone replacement therapy to treat the problems of menopause, such as hot flashes and vaginal dryness, or to prevent osteoporosis. Transdermal Patch (OrthoEvra) is a beige-colored, transdermal patch applied once a week to the abdomen, buttock. Transdermal Contraceptive Patch. Table of Contents; Previous Section; Next Section; References; Publication. Both oral and transdermal estradiol caused a significant decrease in FSH while only transdermal resulted in a significant decrease in LH. Oral estradiol, though not transdermal estradiol, increased serum high density lipoprotein, thyroxine binding protein and growth hormone binding protein. Urinary growth hormone excretion increased after both forms of therapy, while insulin- like growth factor- I and insulin- like growth factor binding protein- 3 remained unchanged. Thus, in girls with Turner's syndrome, estrogen replacement by the transdermal route may have less deleterious effect on hepatic metabolism than oral estrogen.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. Archives
January 2017
Categories |